Discovery Map

This page is reserved for biological or translational claims, not technical capabilities.

Emerging Discovery Themes

Engineered perturbation can reveal hidden host biology

Several projects began as tool-building efforts but exposed deeper mechanisms. Examples include IMMUNE HIERARCHY and ADAR LICENSING.

Antigen abundance is not the whole immune-hierarchy story

The immune-hierarchy work suggests that the source and context of antigen acquisition may reshape adaptive immune outcome beyond simple antigen-level effects.

Replication-defective or silenced viruses may alter APC sampling

A working model from the immune-hierarchy project is that viruses that do not kill cells and spread normally may be sampled by antigen-presenting cells in a more comprehensive and less inflammatory manner, potentially drawing more from virions than infected-cell debris.

RNAi machinery may act as an ADAR1 licensing system in vertebrate infection biology

The ADAR1 licensing project reframes RNAi-associated machinery as potentially repurposed away from canonical antiviral RNAi and toward licensing ADAR1 to resolve or edit RNA substrates during infection.

Respiratory viral systems can be converted into delivery platforms

The delivery programs seek to convert principles learned from respiratory virology into practical vectors with improved payload capacity, airway access, programmability, and therapeutic relevance.

Curation Rule

Every discovery claim should eventually link to: