AI IFN Mimetics

Person

• Abigail Korenek

Goal

Design AI-generated mimetics of type I interferons, especially IFN-beta-like molecules that preserve structural similarity but produce lower or mid-level signaling.

Concept

Wild-type interferon can be too potent/toxic as a therapeutic. A weaker priming molecule might tune antiviral or anticancer responses without full cytokine potency.

TODO

• Add design method, structural model, receptor-binding assumptions, potency assays, ISG readouts, and therapeutic framing.