Project Family Map

This page groups current projects into coherent scientific and platform families. It is intended to prevent the Atlas from becoming a flat list of disconnected projects.

Project family Primary lane Secondary lane Atlas description
Programmable influenza pathogenesis Lane 1 Lane 2 Engineered influenza viruses used to identify viral determinants and cell-state dependencies that separate replication, inflammation, protection, and pathology.
Abortive and cell-restricted immune activation vectors Lane 2 Lane 1 Viral systems designed to trigger selective sensing programs and clarify how immune outcome is encoded in infected tissues.
miRNA logic and cell-type restriction Lane 2 Lane 3 Mature enabling technology that allows viral programs or payloads to operate only in defined cellular contexts.
Sendai-based editing and delivery systems Lane 3 Lane 2 Respiratory vectors developed for gene delivery, editing, and therapeutic payload deployment in airway-relevant settings.
HERMES and related editor delivery work Lane 3 Lane 2 Translational platform efforts focused on payload capacity, airway access, in vivo activity, biodistribution, and benchmarked comparison.
CPIB3 and CAPTURE platform expansion Lane 3 Lane 2 Next-generation respiratory vector development that extends the platform beyond a single backbone and broadens therapeutic utility.
Universal vaccine and antigen hierarchy work Lane 2 Lane 1 Engineered infection programs that reshape immune prioritization and protection, linking viral design to desired adaptive outcomes.
ADAR1 licensing and RNA-processing control Lane 2 Lane 1 An engineering challenge in miRNA silencing revealed a deeper model in which RNAi-associated machinery may license ADAR1 substrate resolution during infection.

Immediate Curation Use

Each project page should declare: